id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_7mmfe6yhzfelrhg3wa6t4ur2ou	Kim Hung Leung	Systematic Investigation of the Relationship between High Myopia and Polymorphisms of theMMP2,TIMP2, andTIMP3Genes by a DNA Pooling Approach	2011.0	30	.pdf	application/pdf	8533	993	69	TIMP3 SNPs were found significantly associated with high myopia by single-marker or haplotype individual DNA samples forming the original pools, and (3) replication of positive SNPs by an In DNA pooling-based initial study, 600 unrelated Southern Han Chinese subjects (Sample Set 1) Positive SNPs from the DNA poolingbased initial screen were confirmed by individual genotyping of the original Sample Set 1 and, if The positive findings (3 SNPs) in the DNA pooling-based initial study were confirmed by individual For Sample Set 2, two SNPs of the TIMP3 gene (rs135029 and rs137485) were genotyped by SNPs were then genotyped for individual samples forming the DNA pools (Sample Set 1) for associated with high myopia (Pasym=0.0178, omnibus test; Sample Set 1, Table 5). "putatively positive" SNPs were genotyped for individual samples forming the original DNA pools. Pooled DNA analysis of tag SNPs in the MMP2, TIMP2 and TIMP3 genes 	./cache/work_7mmfe6yhzfelrhg3wa6t4ur2ou.pdf	./txt/work_7mmfe6yhzfelrhg3wa6t4ur2ou.txt