id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_5oj3wdjaf5huzczpz3nleymux4	Amish Asthana	Biophysical microenvironment and 3D culture physiological relevance	2013.0	8	.pdf	application/pdf	6985	856	62	for cell-based high-throughput screening (HTS) in preclinical drug discovery. cell culture platforms that provide different MEFs that elicit similar Formation of in vivo-like bile canaliculi structures by HepG2 hepatocytes that is only observed in 3D but not 2D culture formats. micrograph of HepG2 cells cultured on 3D porous polystyrene scaffolds (sc) for 21 days [61], exhibiting tight junction (tj) complexes between adjacent cell; The growing in a 3D format are not just 'different,' but are physiologically more relevant, when compared to cells cultured on traditional 2D surfaces. CPR of 3D liver cell cultures. Liver cell studies with different platforms, but similar CPR outcome studies where liver cells were grown in type I, II and III scaffolds (1990) Long-term culture of rat liver cell spheroids in hormonally (1985) Spheroidal aggregate culture of rat liver cells: histotypic (2007) Culture of HepG2 liver cells on three dimensional CPR in liver tissue-derived cells	./cache/work_5oj3wdjaf5huzczpz3nleymux4.pdf	./txt/work_5oj3wdjaf5huzczpz3nleymux4.txt