id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_4sgrybrer5eu5pmhhgtvfr3s3a	Mong Tieng Ee	Leukotriene B4 Mediates Macrophage Influx and Pulmonary Hypertension in Bleomycin-induced Chronic Neonatal Lung Injury	2016.0	11	.pdf	application/pdf	8026	770	58	Leukotriene B4 mediates macrophage influx and pulmonary hypertension in bleomycin-induced chronic neonatal lung injury hypertension in bleomycin-induced chronic neonatal lung injury. Rat pups were exposed to bleomycin (1 mg·kg�1·day�1 ip) or vehicle (control) from postnatal days These studies demonstrated maximal inhibitory effect of SC57461A on lung LTB4 content macrophages (normalized to tissue fraction) secondary to bleomycin were increased by day 7 of exposure (Fig. 2C), to a Exposure to bleomycin for 7 days had no effect on LTB4 content (data not shown); montelukast did not prevent bleomycin-induced PHT, as evidenced by a lack of effect on PVR (Fig. 5A) and Fulton indexes SC57461A completely prevented the bleomycin-induced increase in lung LTB4, which was unaffected by montelukast. being no increase in lung CysLT content secondary to bleomycin exposure (Fig. 3B), CCL4 was found to be significantly Bleomycin-induced pulmonary hypertension was prevented by SC57461A, a leukotriene (LT) A4 hydrolase inhibitor, but not by	./cache/work_4sgrybrer5eu5pmhhgtvfr3s3a.pdf	./txt/work_4sgrybrer5eu5pmhhgtvfr3s3a.txt