id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_3knropq5xbal7kh5gbr3fraxae	Nanette I. Steinle	Variation in the Lamin A/C Gene	2004.0	6	.pdf	application/pdf	6462	656	65	Objective—Metabolic syndrome is associated with increased risk for cardiovascular disease and type 2 diabetes mellitus The lamin A/C (LMNA) gene, mutations of which cause rare syndromes of severe insulin resistance and Diabetes Study, the H566H polymorphism of LMNA was associated with metabolic syndrome diagnosed according to differences in haplotype frequencies among subjects with metabolic syndrome T2DM, IGH, and controls. Metabolic syndrome is characterized by the presence of �3of the following characteristics: abdominal obesity, elevated triglyceride concentrations, low high-density lipoprotein of age.1 Metabolic syndrome is associated with increased risk of severe insulin resistance, diabetes, dyslipidemia, and atherosclerosis,26 making LMNA an excellent positional candidate gene for are associated with diabetes, metabolic syndrome, and related levels), we estimated mean trait levels according to LMNA genotypes, whereas for the qualitative traits (metabolic syndrome, T2DM, LMNA in subjects with diabetes from Amish families, providing evidence for linkage to chromosome 1q21-q24.	./cache/work_3knropq5xbal7kh5gbr3fraxae.pdf	./txt/work_3knropq5xbal7kh5gbr3fraxae.txt