id author title date pages extension mime words sentences flesch summary cache txt work_3ai6k4agffgebddc7pkfr2n2fi K. R. Owen Common Variation in the LMNA Gene (Encoding Lamin A/C) and Type 2 Diabetes: Association Analyses in 9,518 Subjects 2007.0 5 .pdf application/pdf 4592 429 64 Analysis of 2,490 U.K. diabetic case and 2,556 control subjects revealed no significant associations at either genotype or haplotype level: revealed no consistent case-control or family-based associations with LMNA variants. nly a limited number of genes with reproducible evidence of association with type 2 diabetes have been described. U.K. case resource, ascertained for type 2 diabetes diagnosed before age 65 years; and 350 exclusively British/ U.K. control genotype data for LMNA-region SNPs (minor Family-based association tests (Table 3) were performed in all 1,170 members of the full set of 390 parentoffspring trio pedigrees (see online appendix). between LMNA SNPs and type 2 diabetes (data not not associated with type 2 diabetes in any of the samples LMNA SNPs were associated with type 2 diabetes (all P � COMMON VARIATION IN LMNA AND TYPE 2 DIABETES COMMON VARIATION IN LMNA AND TYPE 2 DIABETES ./cache/work_3ai6k4agffgebddc7pkfr2n2fi.pdf ./txt/work_3ai6k4agffgebddc7pkfr2n2fi.txt