id author title date pages extension mime words sentence flesch summary cache txt news-008658 Uncovering a new pathway to halting metastasis | News | Notre Dame News | University of Notre Dame .html text/html 746 22 41 In aggregate, these two cellular changes (SGK-1 activation and PHLPP1 loss) facilitate long-term survival of cancer cells during metastasis.” While more research needs to be completed, the findings suggest that an effective strategy to eliminate metastatic cancer cells with Ras mutations might be to concurrently inhibit SGK-1 activity, thereby blocking energy production, and restore the ability of PHLPP1 to cause cell death. Notre Dame News | University of Notre Dame Skip To Content Skip To Navigation Skip To Search University of Notre Dame Notre Dame News Experts ND in the News Subscribe About Us Home Contact Search Menu Home › News › Uncovering a new pathway to halting metastasis Uncovering a new pathway to halting metastasis Published: August 18, 2016 Author: William G. Gilroy Zachary Schafer Metastasis, the process by which cancer cells leave the primary tumor and spread to other sites in the body, is responsible for more than 90 percent of cancer deaths. cache/news-008658.html txt/news-008658.txt